Amy appeared as one of the main characters in the latest Sonic anime series, Sonic X. Sonic X is Amy's first appearance to the Sonic TV series. In Sonic X, Amy is Sonic's self-proclaimed girlfriend. (I hate to say that really, but I had to...) Like in all of her game appearances, her long term goal is to marry Sonic the Hedgehog and get Sonic to notice her. Her attitude is different in Sonic X, as she is more violent then in her video game appearances.

Sonic's love for Amy Rose is still unclear. In episode 52, when Sonic held up a rose to Amy, in the Japanese version what Sonic said was muted. In the 4Kids English version, he said he will never leave Amy and in the French version, he said he loves Amy.

Sonic also risks his life to save Amy in episode 9, when Amy was drowning and he had to save her even know he CAN'T swim.

Amy in episode 72, willingly risked her life to into saving Sonic in Dark Oak's planet knowing there maybe no way out of that planet.